null

SMILES: COc1c(OCC#C)ccc2OC(CC=C)c3c(ccc4NC(C)(C)C=C(C)c34)-c12

InChI Key: InChIKey=BBNUFIDEQWMAMG-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50124599   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50124599 (5-Allyl-10-methoxy-2,2,4-trimethyl-9-prop-2-ynylox...) Show SMILES COc1c(OCC#C)ccc2OC(CC=C)c3c(ccc4NC(C)(C)C=C(C)c34)-c12 |t:25| Show InChI InChI=1S/C26H27NO3/c1-7-9-19-23-17(10-11-18-22(23)16(3)15-26(4,5)27-18)24-20(30-19)12-13-21(25(24)28-6)29-14-8-2/h2,7,10-13,15,19,27H,1,9,14H2,3-6H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	14	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Binding affinity towards human glucocorticoid receptor (GR) was determined using [3H]-Dexamethasone as radioligand in SF-1 cells				J Med Chem 46: 1016-30 (2003) Article DOI: 10.1021/jm020335m BindingDB Entry DOI: 10.7270/Q2MP52NB
					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50124599 (5-Allyl-10-methoxy-2,2,4-trimethyl-9-prop-2-ynylox...) Show SMILES COc1c(OCC#C)ccc2OC(CC=C)c3c(ccc4NC(C)(C)C=C(C)c34)-c12 |t:25| Show InChI InChI=1S/C26H27NO3/c1-7-9-19-23-17(10-11-18-22(23)16(3)15-26(4,5)27-18)24-20(30-19)12-13-21(25(24)28-6)29-14-8-2/h2,7,10-13,15,19,27H,1,9,14H2,3-6H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.81E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Displacement of [3H]-progesterone from human Progesterone receptor A				J Med Chem 46: 1016-30 (2003) Article DOI: 10.1021/jm020335m BindingDB Entry DOI: 10.7270/Q2MP52NB
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50124599 (5-Allyl-10-methoxy-2,2,4-trimethyl-9-prop-2-ynylox...) Show SMILES COc1c(OCC#C)ccc2OC(CC=C)c3c(ccc4NC(C)(C)C=C(C)c34)-c12 |t:25| Show InChI InChI=1S/C26H27NO3/c1-7-9-19-23-17(10-11-18-22(23)16(3)15-26(4,5)27-18)24-20(30-19)12-13-21(25(24)28-6)29-14-8-2/h2,7,10-13,15,19,27H,1,9,14H2,3-6H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	160	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of dihydrofolate reductase DHFR in Pneumocystis carinii.				J Med Chem 46: 1016-30 (2003) Article DOI: 10.1021/jm020335m BindingDB Entry DOI: 10.7270/Q2MP52NB
					More data for this Ligand-Target Pair