null

SMILES: COc1ccc(C=C)c2OC(CC=C)c3c(ccc4NC(C)(C)C=C(C)c34)-c12

InChI Key: InChIKey=XOSVCJKDUIUUIB-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50124616   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50124616 (5-Allyl-10-methoxy-2,2,4-trimethyl-7-vinyl-2,5-dih...) Show SMILES COc1ccc(C=C)c2OC(CC=C)c3c(ccc4NC(C)(C)C=C(C)c34)-c12 |t:23| Show InChI InChI=1S/C25H27NO2/c1-7-9-20-22-17(11-12-18-21(22)15(3)14-25(4,5)26-18)23-19(27-6)13-10-16(8-2)24(23)28-20/h7-8,10-14,20,26H,1-2,9H2,3-6H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	34	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Binding affinity towards human glucocorticoid receptor (GR) was determined using [3H]-Dexamethasone as radioligand in SF-1 cells				J Med Chem 46: 1016-30 (2003) Article DOI: 10.1021/jm020335m BindingDB Entry DOI: 10.7270/Q2MP52NB
					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50124616 (5-Allyl-10-methoxy-2,2,4-trimethyl-7-vinyl-2,5-dih...) Show SMILES COc1ccc(C=C)c2OC(CC=C)c3c(ccc4NC(C)(C)C=C(C)c34)-c12 |t:23| Show InChI InChI=1S/C25H27NO2/c1-7-9-20-22-17(11-12-18-21(22)15(3)14-25(4,5)26-18)23-19(27-6)13-10-16(8-2)24(23)28-20/h7-8,10-14,20,26H,1-2,9H2,3-6H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	450	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Displacement of [3H]-progesterone from human Progesterone receptor A				J Med Chem 46: 1016-30 (2003) Article DOI: 10.1021/jm020335m BindingDB Entry DOI: 10.7270/Q2MP52NB
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50124616 (5-Allyl-10-methoxy-2,2,4-trimethyl-7-vinyl-2,5-dih...) Show SMILES COc1ccc(C=C)c2OC(CC=C)c3c(ccc4NC(C)(C)C=C(C)c34)-c12 |t:23| Show InChI InChI=1S/C25H27NO2/c1-7-9-20-22-17(11-12-18-21(22)15(3)14-25(4,5)26-18)23-19(27-6)13-10-16(8-2)24(23)28-20/h7-8,10-14,20,26H,1-2,9H2,3-6H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	156	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Binding affinity towards human glucocorticoid receptor (GR) was determined using [3H]-Dexamethasone as radioligand in SF-1 cells				J Med Chem 46: 1016-30 (2003) Article DOI: 10.1021/jm020335m BindingDB Entry DOI: 10.7270/Q2MP52NB
					More data for this Ligand-Target Pair