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SMILES: Cc1c(Cl)nc(nc1NCc1ccon1)C1CC1

InChI Key: InChIKey=UIFFSZFOSHYWBP-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50124632   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A


(Homo sapiens (Human))		BDBM50124632
PNG
(CHEMBL3622882)
Show SMILES Cc1c(Cl)nc(nc1NCc1ccon1)C1CC1
Show InChI InChI=1S/C12H13ClN4O/c1-7-10(13)15-12(8-2-3-8)16-11(7)14-6-9-4-5-18-17-9/h4-5,8H,2-3,6H2,1H3,(H,14,15,16)
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PubMed
 810n/an/an/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Inhibition of human PDE10A2 transfected in AD293 cells by IMAP FP assay

J Med Chem 58: 7888-94 (2015)


BindingDB Entry DOI: 10.7270/Q26Q202C
More data for this
Ligand-Target Pair