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SMILES: Cc1ncc(CNc2nc(nc(Cl)c2C)C2CC2)s1

InChI Key: InChIKey=PTJWCECUGBETAA-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50124635   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A


(Homo sapiens (Human))		BDBM50124635
PNG
(CHEMBL3622885)
Show SMILES Cc1ncc(CNc2nc(nc(Cl)c2C)C2CC2)s1
Show InChI InChI=1S/C13H15ClN4S/c1-7-11(14)17-13(9-3-4-9)18-12(7)16-6-10-5-15-8(2)19-10/h5,9H,3-4,6H2,1-2H3,(H,16,17,18)
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PubMed
 26n/an/an/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Inhibition of human PDE10A2 transfected in AD293 cells by IMAP FP assay

J Med Chem 58: 7888-94 (2015)


BindingDB Entry DOI: 10.7270/Q26Q202C
More data for this
Ligand-Target Pair