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SMILES: CCOC(=O)c1c(N)sc(C(=O)Nc2cccc(c2)C#N)c1C

InChI Key: InChIKey=JQXQQBCAQWJDTA-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50124904   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Histone-lysine N-methyltransferase SETD7


(Homo sapiens (Human))		BDBM50124904
PNG
(CHEMBL3623769)
Show SMILES CCOC(=O)c1c(N)sc(C(=O)Nc2cccc(c2)C#N)c1C
Show InChI InChI=1S/C16H15N3O3S/c1-3-22-16(21)12-9(2)13(23-14(12)18)15(20)19-11-6-4-5-10(7-11)8-17/h4-7H,3,18H2,1-2H3,(H,19,20)
PDB

UniProtKB/SwissProt

antibodypedia
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PC cid
PC sid
UniChem

Patents
PubMed
n/an/a 6.16E+4n/an/an/an/an/an/a



Shanghai University

Curated by ChEMBL


Assay Description
Competitive inhibition of SET7 (unknown origin) after 60 mins by AlphaLISA method in presence of SAM

J Med Chem 58: 8166-81 (2015)


BindingDB Entry DOI: 10.7270/Q2TF005S
More data for this
Ligand-Target Pair