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SMILES: CN(CCc1ccccc1)c1ccc(cn1)C(Cc1cc[n+]([O-])cc1)c1ccc(OC(F)F)c(OC(F)F)c1

InChI Key: InChIKey=FJJAEUXXNHLBHF-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50125067   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
cAMP-specific 3',5'-cyclic phosphodiesterase 4A


(Homo sapiens (Human))		BDBM50125067
PNG
(CHEMBL351007 | {5-[1-(3,4-Bis-difluoromethoxy-phen...)
Show SMILES CN(CCc1ccccc1)c1ccc(cn1)C(Cc1cc[n+]([O-])cc1)c1ccc(OC(F)F)c(OC(F)F)c1
Show InChI InChI=1S/C29H27F4N3O3/c1-35(14-11-20-5-3-2-4-6-20)27-10-8-23(19-34-27)24(17-21-12-15-36(37)16-13-21)22-7-9-25(38-28(30)31)26(18-22)39-29(32)33/h2-10,12-13,15-16,18-19,24,28-29H,11,14,17H2,1H3
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KEGG

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PC cid
PC sid
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Patents

Similars
PubMed
n/an/a 5.80n/an/an/an/an/an/a



Merck Frosst Centre for Therapeutic Research

Curated by ChEMBL


Assay Description
Inhibitory activity against human PDE4A expressed isoform using construct representing the common region of spliced variants as GST-fusion protein in...

Bioorg Med Chem Lett 13: 741-4 (2003)


BindingDB Entry DOI: 10.7270/Q2PG1R3G
More data for this
Ligand-Target Pair