Found 3 hits for monomerid = 50125195 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Integrin beta-2/Leukocyte adhesion glycoprotein LFA-1 alpha
(Homo sapiens (Human)) | BDBM50125195
((S)-2-(2-Bromo-benzoylamino)-3-(3H-imidazol-4-yl)-...)Show InChI InChI=1S/C13H12BrN3O3/c14-10-4-2-1-3-9(10)12(18)17-11(13(19)20)5-8-6-15-7-16-8/h1-4,6-7,11H,5H2,(H,15,16)(H,17,18)(H,19,20)/t11-/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 750 | n/a | n/a | n/a | n/a | n/a | n/a |
Sunesis Pharmaceuticals, Inc
Curated by ChEMBL
| Assay Description Inhibition of LFA1/ICAM1 interaction by ELISA |
Bioorg Med Chem Lett 21: 307-10 (2010)
Article DOI: 10.1016/j.bmcl.2010.11.014 BindingDB Entry DOI: 10.7270/Q2WW7HXM |
More data for this Ligand-Target Pair | |
Integrin beta-2/Intercellular adhesion molecule-1 /Leukocyte adhesion glycoprotein LFA-1 alpha
(Homo sapiens (Human)) | BDBM50125195
((S)-2-(2-Bromo-benzoylamino)-3-(3H-imidazol-4-yl)-...)Show InChI InChI=1S/C13H12BrN3O3/c14-10-4-2-1-3-9(10)12(18)17-11(13(19)20)5-8-6-15-7-16-8/h1-4,6-7,11H,5H2,(H,15,16)(H,17,18)(H,19,20)/t11-/m0/s1 | PDB
UniProtKB/SwissProt UniProtKB/TrEMBL
antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 750 | n/a | n/a | n/a | n/a | n/a | n/a |
Genentech
Curated by ChEMBL
| Assay Description Inhibitory activity against association of LFA-1 with intercellular adhesion molecule 1 |
Bioorg Med Chem Lett 14: 2055-9 (2004)
Article DOI: 10.1016/j.bmcl.2004.02.046 BindingDB Entry DOI: 10.7270/Q2T1532F |
More data for this Ligand-Target Pair | |
Integrin beta-2/Intercellular adhesion molecule-1 /Leukocyte adhesion glycoprotein LFA-1 alpha
(Homo sapiens (Human)) | BDBM50125195
((S)-2-(2-Bromo-benzoylamino)-3-(3H-imidazol-4-yl)-...)Show InChI InChI=1S/C13H12BrN3O3/c14-10-4-2-1-3-9(10)12(18)17-11(13(19)20)5-8-6-15-7-16-8/h1-4,6-7,11H,5H2,(H,15,16)(H,17,18)(H,19,20)/t11-/m0/s1 | PDB
UniProtKB/SwissProt UniProtKB/TrEMBL
antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| n/a | n/a | 750 | n/a | n/a | n/a | n/a | n/a | n/a |
Genentech
Curated by ChEMBL
| Assay Description Potency on ETA receptor assessed by inhibition of the contraction induced by ET-1 in rat aortic rings |
Bioorg Med Chem Lett 13: 1015-8 (2003)
BindingDB Entry DOI: 10.7270/Q2K35V6V |
More data for this Ligand-Target Pair | |