BDBM50125309 (S)-3-[3'-(3-Propyl-ureido)-biphenyl-4-yloxy]-2-(2,4,6-trimethyl-benzenesulfonylamino)-propionic acid::CHEMBL11107
SMILES: CCCNC(=O)Nc1cccc(c1)-c1ccc(OC[C@H](NS(=O)(=O)c2c(C)cc(C)cc2C)C(O)=O)cc1
InChI Key: InChIKey=SXTLBFQXNNGAPB-VWLOTQADSA-N
Data: 1 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
ITGAV/ITGB3 (Homo sapiens (Human)) | BDBM50125309 ((S)-3-[3'-(3-Propyl-ureido)-biphenyl-4-yloxy]-2-(2...) | PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents | PubMed | 4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Bayer AG Curated by ChEMBL | Assay Description Binding affinity towards vitronectin receptor (alpha V-beta3) was determined | Bioorg Med Chem Lett 13: 1071-4 (2003) BindingDB Entry DOI: 10.7270/Q2S46T44 | |||||||||||
More data for this Ligand-Target Pair |