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SMILES: FC(F)(F)c1ccc(cc1)-c1cccn(C(Cn2ccnc2)c2ccccc2)c1=O

InChI Key: InChIKey=KCGULYCKVHGSFH-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50125443   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Kappa-type opioid receptor


(Homo sapiens (Human))		BDBM50125443
PNG
(1-(2-Imidazol-1-yl-1-phenyl-ethyl)-3-(4-trifluorom...)
Show SMILES FC(F)(F)c1ccc(cc1)-c1cccn(C(Cn2ccnc2)c2ccccc2)c1=O
Show InChI InChI=1S/C23H18F3N3O/c24-23(25,26)19-10-8-17(9-11-19)20-7-4-13-29(22(20)30)21(15-28-14-12-27-16-28)18-5-2-1-3-6-18/h1-14,16,21H,15H2
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n/an/a>1.00E+4n/an/an/an/an/an/a



AstraZeneca R&D

Curated by ChEMBL


Assay Description
Inhibition of [125I]-(D-Pro10)-Dynorphin A binding to human kappa opioid receptor from membranes of HEK293 cells

Bioorg Med Chem Lett 13: 1141-5 (2003)


BindingDB Entry DOI: 10.7270/Q24J0DH2
More data for this
Ligand-Target Pair