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SMILES: O=c1c(nccn1C(CN1CCCC1)c1ccccc1)-c1ccccc1

InChI Key: InChIKey=OCWVGZOWVIJLAB-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50125453   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Kappa-type opioid receptor


(Homo sapiens (Human))		BDBM50125453
PNG
(3-Phenyl-1-(1-phenyl-2-pyrrolidin-1-yl-ethyl)-1H-p...)
Show SMILES O=c1c(nccn1C(CN1CCCC1)c1ccccc1)-c1ccccc1
Show InChI InChI=1S/C22H23N3O/c26-22-21(19-11-5-2-6-12-19)23-13-16-25(22)20(17-24-14-7-8-15-24)18-9-3-1-4-10-18/h1-6,9-13,16,20H,7-8,14-15,17H2
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PC cid
PC sid
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PubMed
n/an/a 2.45E+3n/an/an/an/an/an/a



AstraZeneca R&D

Curated by ChEMBL


Assay Description
Inhibition of [125I]-(D-Pro10)-Dynorphin A binding to human kappa opioid receptor from membranes of HEK293 cells

Bioorg Med Chem Lett 13: 1141-5 (2003)


BindingDB Entry DOI: 10.7270/Q24J0DH2
More data for this
Ligand-Target Pair