BDBM50125464 1-(1-Phenyl-2-pyrrolidin-1-yl-ethyl)-3-p-tolylamino-1H-pyridin-2-one::CHEMBL14905

SMILES: Cc1ccc(Nc2cccn(C(CN3CCCC3)c3ccccc3)c2=O)cc1

InChI Key: InChIKey=JLCLSMWGDDQREJ-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50125464   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Kappa-type opioid receptor (Homo sapiens (Human))	BDBM50125464 (1-(1-Phenyl-2-pyrrolidin-1-yl-ethyl)-3-p-tolylamin...) Show SMILES Cc1ccc(Nc2cccn(C(CN3CCCC3)c3ccccc3)c2=O)cc1 Show InChI InChI=1S/C24H27N3O/c1-19-11-13-21(14-12-19)25-22-10-7-17-27(24(22)28)23(18-26-15-5-6-16-26)20-8-3-2-4-9-20/h2-4,7-14,17,23,25H,5-6,15-16,18H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	94	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca R&D Curated by ChEMBL					Assay Description Inhibition of [125I]-(D-Pro10)-Dynorphin A binding to human kappa opioid receptor from membranes of HEK293 cells				Bioorg Med Chem Lett 13: 1141-5 (2003) BindingDB Entry DOI: 10.7270/Q24J0DH2
					More data for this Ligand-Target Pair
Delta-type opioid receptor (Homo sapiens (Human))	BDBM50125464 (1-(1-Phenyl-2-pyrrolidin-1-yl-ethyl)-3-p-tolylamin...) Show SMILES Cc1ccc(Nc2cccn(C(CN3CCCC3)c3ccccc3)c2=O)cc1 Show InChI InChI=1S/C24H27N3O/c1-19-11-13-21(14-12-19)25-22-10-7-17-27(24(22)28)23(18-26-15-5-6-16-26)20-8-3-2-4-9-20/h2-4,7-14,17,23,25H,5-6,15-16,18H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca R&D Curated by ChEMBL					Assay Description Inhibition of [125I]-Deltorphin binding to human delta opioid receptor from membranes of HEK293 cells				Bioorg Med Chem Lett 13: 1141-5 (2003) BindingDB Entry DOI: 10.7270/Q24J0DH2
					More data for this Ligand-Target Pair