BDBM50125528 CHEMBL16518::N-Cyclohexylmethyl-2-methoxy-benzamide

SMILES: COc1ccccc1C(=O)NCC1CCCCC1

InChI Key: InChIKey=BRPFZJZGVQJNBA-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50125528   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Voltage-gated potassium channel (Homo sapiens (Human))	BDBM50125528 (CHEMBL16518 | N-Cyclohexylmethyl-2-methoxy-benzami...) Show SMILES COc1ccccc1C(=O)NCC1CCCCC1 Show InChI InChI=1S/C15H21NO2/c1-18-14-10-6-5-9-13(14)15(17)16-11-12-7-3-2-4-8-12/h5-6,9-10,12H,2-4,7-8,11H2,1H3,(H,16,17)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of Kv1.3 ion channel. Measured in the Rb_Kv assay: [86Rb+] efflux from CHO cells stably transfected with Kv1.3 channel.				Bioorg Med Chem Lett 13: 1161-4 (2003) BindingDB Entry DOI: 10.7270/Q2W09596
					More data for this Ligand-Target Pair