BDBM50125822 1-Hydroxy-5-isobutyl-3-isobutylidene-3H-pyrazine-2,6-dione::1-hydroxy-5-isobutyl-3-(2-methylpropylidene)pyrazine-2,6(1H,3H)-dione::CHEMBL16320

SMILES: CC(C)C=c1[nH]c(=CC(C)C)c(=O)n(O)c1=O

InChI Key: InChIKey=TUQNIQJUVAGXTK-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50125822   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Polymerase acidic protein (Hepatitis C virus)	BDBM50125822 (1-Hydroxy-5-isobutyl-3-isobutylidene-3H-pyrazine-2...) Show SMILES CC(C)C=c1[nH]c(=CC(C)C)c(=O)n(O)c1=O |w:3.2,7.7| Show InChI InChI=1S/C12H18N2O3/c1-7(2)5-9-11(15)14(17)12(16)10(13-9)6-8(3)4/h5-8,13,17H,1-4H3	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Roche Discovery Welwyn Curated by ChEMBL					Assay Description Inhibitory concentration against cap-dependent endonuclease activity of influenza virus RNP				J Med Chem 46: 1153-64 (2003) Article DOI: 10.1021/jm020334u BindingDB Entry DOI: 10.7270/Q22J6B6V
					More data for this Ligand-Target Pair
Polymerase acidic protein (Hepatitis C virus)	BDBM50125822 (1-Hydroxy-5-isobutyl-3-isobutylidene-3H-pyrazine-2...) Show SMILES CC(C)C=c1[nH]c(=CC(C)C)c(=O)n(O)c1=O |w:3.2,7.7| Show InChI InChI=1S/C12H18N2O3/c1-7(2)5-9-11(15)14(17)12(16)10(13-9)6-8(3)4/h5-8,13,17H,1-4H3	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Shandong University Curated by ChEMBL					Assay Description Inhibition of influenza A virus (A/PR/8/34) N-terminal PA endonuclease using 880 nucleotide ALMV cap1 primer RNA as substrate				J Med Chem 60: 3533-3551 (2017) Article DOI: 10.1021/acs.jmedchem.6b01227 BindingDB Entry DOI: 10.7270/Q2VQ34XH
					More data for this Ligand-Target Pair
Polymerase acidic protein (Hepatitis C virus)	BDBM50125822 (1-Hydroxy-5-isobutyl-3-isobutylidene-3H-pyrazine-2...) Show SMILES CC(C)C=c1[nH]c(=CC(C)C)c(=O)n(O)c1=O |w:3.2,7.7| Show InChI InChI=1S/C12H18N2O3/c1-7(2)5-9-11(15)14(17)12(16)10(13-9)6-8(3)4/h5-8,13,17H,1-4H3	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	5.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of cap 1 ALMV primed Influenza transcriptase				J Org Chem 66: 5504-16 (2001) BindingDB Entry DOI: 10.7270/Q298882D
					More data for this Ligand-Target Pair