BDBM50126107 CHEMBL3627818

SMILES: COc1ccc(cc1)-n1c(CCN2C(=O)c3c(C2=O)c(Cl)ccc3Cl)nc2ccccc2c1=O

InChI Key: InChIKey=WVNSIWIDCVGICE-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50126107   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A (Homo sapiens (Human))	BDBM50126107 (CHEMBL3627818) Show SMILES COc1ccc(cc1)-n1c(CCN2C(=O)c3c(C2=O)c(Cl)ccc3Cl)nc2ccccc2c1=O Show InChI InChI=1S/C25H17Cl2N3O4/c1-34-15-8-6-14(7-9-15)30-20(28-19-5-3-2-4-16(19)23(30)31)12-13-29-24(32)21-17(26)10-11-18(27)22(21)25(29)33/h2-11H,12-13H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	6.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of PDE10A (unknown origin)				Bioorg Med Chem Lett 25: 4893-8 (2015) BindingDB Entry DOI: 10.7270/Q2RJ4M9Z
					More data for this Ligand-Target Pair