BDBM50126114 CHEMBL3627743

SMILES: Cc1ccc(cc1)-c1cn(CCC[C@H](NC(=O)OCC2c3ccccc3-c3ccccc23)C(O)=O)nn1

InChI Key: InChIKey=WUUBAZLFFIBOOY-SANMLTNESA-N

Data: 1 KI  1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50126114   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
MDM2-MDMX (Homo sapiens (Human))	BDBM50126114 (CHEMBL3627743) Show SMILES Cc1ccc(cc1)-c1cn(CCC[C@H](NC(=O)OCC2c3ccccc3-c3ccccc23)C(O)=O)nn1 |r| Show InChI InChI=1S/C29H28N4O4/c1-19-12-14-20(15-13-19)27-17-33(32-31-27)16-6-11-26(28(34)35)30-29(36)37-18-25-23-9-4-2-7-21(23)22-8-3-5-10-24(22)25/h2-5,7-10,12-15,17,25-26H,6,11,16,18H2,1H3,(H,30,36)(H,34,35)/t26-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	3.05E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of East Anglia Curated by ChEMBL					Assay Description Inhibition of human MDM2 (17 to 125 residues) assessed as apparent inhibition constant for reduction in MDM2 interaction with FAM-LTFEHYWAQLTS-CONH2 ...				Bioorg Med Chem Lett 25: 4878-80 (2015) BindingDB Entry DOI: 10.7270/Q2MS3VK7
					More data for this Ligand-Target Pair
MDM2-MDMX (Homo sapiens (Human))	BDBM50126114 (CHEMBL3627743) Show SMILES Cc1ccc(cc1)-c1cn(CCC[C@H](NC(=O)OCC2c3ccccc3-c3ccccc23)C(O)=O)nn1 |r| Show InChI InChI=1S/C29H28N4O4/c1-19-12-14-20(15-13-19)27-17-33(32-31-27)16-6-11-26(28(34)35)30-29(36)37-18-25-23-9-4-2-7-21(23)22-8-3-5-10-24(22)25/h2-5,7-10,12-15,17,25-26H,6,11,16,18H2,1H3,(H,30,36)(H,34,35)/t26-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.43E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of East Anglia Curated by ChEMBL					Assay Description Inhibition of human MDM2 (17 to 125 residues) assessed as reduction in MDM2 interaction with FAM-LTFEHYWAQLTS-CONH2 peptide incubated for 30 mins by ...				Bioorg Med Chem Lett 25: 4878-80 (2015) BindingDB Entry DOI: 10.7270/Q2MS3VK7
					More data for this Ligand-Target Pair