BDBM50126250 CHEMBL26192::N-[2,4-Dichloro-3-(2-methyl-quinolin-8-yloxymethyl)-phenyl]-N-methyl-2-[1-methyl-5-(4-sulfamoyl-benzoyl)-1H-pyrrol-2-yl]-acetamide

SMILES: CN(C(=O)Cc1ccc(C(=O)c2ccc(cc2)S(N)(=O)=O)n1C)c1ccc(Cl)c(COc2cccc3ccc(C)nc23)c1Cl

InChI Key: InChIKey=QAJPBRPMSJFPGR-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50126250   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
BDKRB2 (Homo sapiens (Human))	BDBM50126250 (CHEMBL26192 | N-[2,4-Dichloro-3-(2-methyl-quinolin...) Show SMILES CN(C(=O)Cc1ccc(C(=O)c2ccc(cc2)S(N)(=O)=O)n1C)c1ccc(Cl)c(COc2cccc3ccc(C)nc23)c1Cl Show InChI InChI=1S/C32H28Cl2N4O5S/c1-19-7-8-20-5-4-6-28(31(20)36-19)43-18-24-25(33)14-16-26(30(24)34)38(3)29(39)17-22-11-15-27(37(22)2)32(40)21-9-12-23(13-10-21)44(35,41)42/h4-16H,17-18H2,1-3H3,(H2,35,41,42)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	76	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Binding affinity towards human bradykinin receptor B2				Bioorg Med Chem Lett 13: 1341-4 (2003) BindingDB Entry DOI: 10.7270/Q2HM57T1
					More data for this Ligand-Target Pair