BDBM50126336 4-{[(4-Cyano-3-naphthalen-1-yl-phenyl)-(3-methyl-3H-imidazol-4-ylmethyl)-amino]-methyl}-pyridine-2-carbonitrile::CHEMBL282959

SMILES: Cn1cncc1CN(Cc1ccnc(c1)C#N)c1ccc(C#N)c(c1)-c1cccc2ccccc12

InChI Key: InChIKey=UOFUHTKNEZKVSV-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50126336   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein Farnesyltransferase (PFT) (Bos taurus (bovine))	BDBM50126336 (4-{[(4-Cyano-3-naphthalen-1-yl-phenyl)-(3-methyl-3...) Show SMILES Cn1cncc1CN(Cc1ccnc(c1)C#N)c1ccc(C#N)c(c1)-c1cccc2ccccc12 Show InChI InChI=1S/C29H22N6/c1-34-20-32-17-26(34)19-35(18-21-11-12-33-24(13-21)16-31)25-10-9-23(15-30)29(14-25)28-8-4-6-22-5-2-3-7-27(22)28/h2-14,17,20H,18-19H2,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	0.370	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description In vitro inhibition of geranylgeranyltransferase.				Bioorg Med Chem Lett 13: 1367-71 (2003) BindingDB Entry DOI: 10.7270/Q20K27ZP
					More data for this Ligand-Target Pair
Geranylgeranyl Transferase (GGTase-I) (Bos taurus (bovine))	BDBM50126336 (4-{[(4-Cyano-3-naphthalen-1-yl-phenyl)-(3-methyl-3...) Show SMILES Cn1cncc1CN(Cc1ccnc(c1)C#N)c1ccc(C#N)c(c1)-c1cccc2ccccc12 Show InChI InChI=1S/C29H22N6/c1-34-20-32-17-26(34)19-35(18-21-11-12-33-24(13-21)16-31)25-10-9-23(15-30)29(14-25)28-8-4-6-22-5-2-3-7-27(22)28/h2-14,17,20H,18-19H2,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	650	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description In vitro inhibitory activity of the compound against farnesyltransferase (FTase)				Bioorg Med Chem Lett 13: 1367-71 (2003) BindingDB Entry DOI: 10.7270/Q20K27ZP
					More data for this Ligand-Target Pair