BDBM50126340 4-[(3-Cyano-benzyl)-(3-methyl-3H-imidazol-4-ylmethyl)-amino]-2-naphthalen-1-yl-benzonitrile::CHEMBL431884

SMILES: Cn1cncc1CN(Cc1cccc(Cl)c1)c1ccc(C#N)c(c1)-c1cccc2ccccc12

InChI Key: InChIKey=UECDXBYNFSLTKG-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50126340   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein Farnesyltransferase (PFT) (Bos taurus (bovine))	BDBM50126340 (4-[(3-Cyano-benzyl)-(3-methyl-3H-imidazol-4-ylmeth...) Show SMILES Cn1cncc1CN(Cc1cccc(Cl)c1)c1ccc(C#N)c(c1)-c1cccc2ccccc12 Show InChI InChI=1S/C29H23ClN4/c1-33-20-32-17-26(33)19-34(18-21-6-4-9-24(30)14-21)25-13-12-23(16-31)29(15-25)28-11-5-8-22-7-2-3-10-27(22)28/h2-15,17,20H,18-19H2,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	0.450	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description In vitro inhibitory activity of the compound against farnesyltransferase (FTase)				Bioorg Med Chem Lett 13: 1367-71 (2003) BindingDB Entry DOI: 10.7270/Q20K27ZP
					More data for this Ligand-Target Pair
Geranylgeranyl Transferase (GGTase-I) (Bos taurus (bovine))	BDBM50126340 (4-[(3-Cyano-benzyl)-(3-methyl-3H-imidazol-4-ylmeth...) Show SMILES Cn1cncc1CN(Cc1cccc(Cl)c1)c1ccc(C#N)c(c1)-c1cccc2ccccc12 Show InChI InChI=1S/C29H23ClN4/c1-33-20-32-17-26(33)19-34(18-21-6-4-9-24(30)14-21)25-13-12-23(16-31)29(15-25)28-11-5-8-22-7-2-3-10-27(22)28/h2-15,17,20H,18-19H2,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	230	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description In vitro inhibitory activity of the compound against farnesyltransferase (FTase)				Bioorg Med Chem Lett 13: 1367-71 (2003) BindingDB Entry DOI: 10.7270/Q20K27ZP
					More data for this Ligand-Target Pair