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BDBM50126408 CHEMBL30381::N*1*-[7-(4-Diethylamino-phenyl)-[1,6]naphthyridin-5-yl]-propane-1,3-diamine

SMILES: CCN(CC)c1ccc(cc1)-c1cc2ncccc2c(NCCCN)n1

InChI Key: InChIKey=KKLWCWBLIPONGL-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50126408   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Tyrosine-protein kinase SYK


(Homo sapiens (Human))
BDBM50126408
PNG
(CHEMBL30381 | N*1*-[7-(4-Diethylamino-phenyl)-[1,6...)
Show SMILES CCN(CC)c1ccc(cc1)-c1cc2ncccc2c(NCCCN)n1
Show InChI InChI=1S/C21H27N5/c1-3-26(4-2)17-10-8-16(9-11-17)19-15-20-18(7-5-13-23-20)21(25-19)24-14-6-12-22/h5,7-11,13,15H,3-4,6,12,14,22H2,1-2H3,(H,24,25)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
PubMed
n/an/a 20n/an/an/an/an/an/a



Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL


Assay Description
Inhibitory activity against spleen tyrosine kinase (SYK)


Bioorg Med Chem Lett 13: 1415-8 (2003)


BindingDB Entry DOI: 10.7270/Q2MC8ZCJ
More data for this
Ligand-Target Pair