BDBM50126430 CHEMBL284590::N*1*-[7-(4-Methylsulfanyl-phenyl)-[1,6]naphthyridin-5-yl]-propane-1,3-diamine::N1-(7-(4-(methylthio)phenyl)-1,6-naphthyridin-5-yl)propane-1,3-diamine

SMILES: CSc1ccc(cc1)-c1cc2ncccc2c(NCCCN)n1

InChI Key: InChIKey=NSHOVULIECYORC-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50126430   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase SYK (Homo sapiens (Human))	BDBM50126430 (CHEMBL284590 | N*1*-[7-(4-Methylsulfanyl-phenyl)-[...) Show SMILES CSc1ccc(cc1)-c1cc2ncccc2c(NCCCN)n1 Show InChI InChI=1S/C18H20N4S/c1-23-14-7-5-13(6-8-14)16-12-17-15(4-2-10-20-17)18(22-16)21-11-3-9-19/h2,4-8,10,12H,3,9,11,19H2,1H3,(H,21,22)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	34	n/a	n/a	n/a	n/a	n/a	n/a
Sichuan University Curated by ChEMBL					Assay Description Inhibition of recombinant Syk (unknown origin)				Bioorg Med Chem Lett 19: 1944-9 (2009) Article DOI: 10.1016/j.bmcl.2009.02.049 BindingDB Entry DOI: 10.7270/Q2WM1D98
					More data for this Ligand-Target Pair
Tyrosine-protein kinase SYK (Homo sapiens (Human))	BDBM50126430 (CHEMBL284590 | N*1*-[7-(4-Methylsulfanyl-phenyl)-[...) Show SMILES CSc1ccc(cc1)-c1cc2ncccc2c(NCCCN)n1 Show InChI InChI=1S/C18H20N4S/c1-23-14-7-5-13(6-8-14)16-12-17-15(4-2-10-20-17)18(22-16)21-11-3-9-19/h2,4-8,10,12H,3,9,11,19H2,1H3,(H,21,22)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	34	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Curated by ChEMBL					Assay Description Inhibitory activity against spleen tyrosine kinase (SYK)				Bioorg Med Chem Lett 13: 1415-8 (2003) BindingDB Entry DOI: 10.7270/Q2MC8ZCJ
					More data for this Ligand-Target Pair