BDBM50126439 CHEMBL30774::[7-(4-Methoxy-phenyl)-[1,6]naphthyridin-5-yl]-methyl-amine

SMILES: CNc1nc(cc2ncccc12)-c1ccc(OC)cc1

InChI Key: InChIKey=HXMCZIXCUWAZEK-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50126439   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase SYK (Homo sapiens (Human))	BDBM50126439 (CHEMBL30774 | [7-(4-Methoxy-phenyl)-[1,6]naphthyri...) Show SMILES CNc1nc(cc2ncccc12)-c1ccc(OC)cc1 Show InChI InChI=1S/C16H15N3O/c1-17-16-13-4-3-9-18-15(13)10-14(19-16)11-5-7-12(20-2)8-6-11/h3-10H,1-2H3,(H,17,19)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	490	n/a	n/a	n/a	n/a	n/a	n/a
Rigel, Inc. Curated by ChEMBL					Assay Description Inhibition of SYK				J Med Chem 55: 3614-43 (2012) Article DOI: 10.1021/jm201271b BindingDB Entry DOI: 10.7270/Q2NZ88RC
					More data for this Ligand-Target Pair
Tyrosine-protein kinase SYK (Homo sapiens (Human))	BDBM50126439 (CHEMBL30774 | [7-(4-Methoxy-phenyl)-[1,6]naphthyri...) Show SMILES CNc1nc(cc2ncccc12)-c1ccc(OC)cc1 Show InChI InChI=1S/C16H15N3O/c1-17-16-13-4-3-9-18-15(13)10-14(19-16)11-5-7-12(20-2)8-6-11/h3-10H,1-2H3,(H,17,19)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	490	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Curated by ChEMBL					Assay Description Inhibitory activity against spleen tyrosine kinase (SYK)				Bioorg Med Chem Lett 13: 1415-8 (2003) BindingDB Entry DOI: 10.7270/Q2MC8ZCJ
					More data for this Ligand-Target Pair