BDBM50126477 2-(4-Naphthalen-1-yl-piperazin-1-ylmethyl)-tetrahydro-imidazo[1,5-a]pyridine-1,3-dione::CHEMBL445055

SMILES: Oc1c2CCCCn2c(=O)n1CN1CCN(CC1)c1cccc2ccccc12

InChI Key: InChIKey=RVLIXCVTIMGVDX-UHFFFAOYSA-N

Data: 3 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50126477   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50126477 (2-(4-Naphthalen-1-yl-piperazin-1-ylmethyl)-tetrahy...) Show SMILES Oc1c2CCCCn2c(=O)n1CN1CCN(CC1)c1cccc2ccccc12 Show InChI InChI=1S/C22H26N4O2/c27-21-20-9-3-4-11-25(20)22(28)26(21)16-23-12-14-24(15-13-23)19-10-5-7-17-6-1-2-8-18(17)19/h1-2,5-8,10,27H,3-4,9,11-16H2	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	5.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universidad Complutense Curated by ChEMBL					Assay Description Binding affinity of the compound towards 5-HT 1A receptor in rat cerebral cortex membranes using [3H]-8-OH-DPAT as radioligand				Bioorg Med Chem Lett 13: 1429-32 (2003) BindingDB Entry DOI: 10.7270/Q2BV7FZX
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50126477 (2-(4-Naphthalen-1-yl-piperazin-1-ylmethyl)-tetrahy...) Show SMILES Oc1c2CCCCn2c(=O)n1CN1CCN(CC1)c1cccc2ccccc12 Show InChI InChI=1S/C22H26N4O2/c27-21-20-9-3-4-11-25(20)22(28)26(21)16-23-12-14-24(15-13-23)19-10-5-7-17-6-1-2-8-18(17)19/h1-2,5-8,10,27H,3-4,9,11-16H2	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	5.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro inhibition of [3H]8-OH-DPAT binding to 5-hydroxytryptamine 1A receptor in rat cerebral cortex membranes				J Med Chem 48: 2548-2558 (2005) Article DOI: 10.1021/jm048999e BindingDB Entry DOI: 10.7270/Q23F4PNB
					More data for this Ligand-Target Pair
Alpha-1 Adrenergic Receptor/ adrenergic receptor/ adrenergic receptor (Rattus norvegicus (rat)-Rattus norvegicus (Rat))	BDBM50126477 (2-(4-Naphthalen-1-yl-piperazin-1-ylmethyl)-tetrahy...) Show SMILES Oc1c2CCCCn2c(=O)n1CN1CCN(CC1)c1cccc2ccccc12 Show InChI InChI=1S/C22H26N4O2/c27-21-20-9-3-4-11-25(20)22(28)26(21)16-23-12-14-24(15-13-23)19-10-5-7-17-6-1-2-8-18(17)19/h1-2,5-8,10,27H,3-4,9,11-16H2	Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universidad Complutense Curated by ChEMBL					Assay Description Binding affinity towards Alpha-1 adrenergic receptor in rat cerebral cortex membranes using [3H]prazosin as radioligand				Bioorg Med Chem Lett 13: 1429-32 (2003) BindingDB Entry DOI: 10.7270/Q2BV7FZX
					More data for this Ligand-Target Pair