BDBM50126481 2-[4-(1H-Benzoimidazol-4-yl)-piperazin-1-ylmethyl]-tetrahydro-pyrrolo[1,2-c]imidazole-1,3-dione::CHEMBL33258
SMILES: Oc1c2CCCn2c(=O)n1CN1CCN(CC1)c1cccc2[nH]cnc12
InChI Key: InChIKey=ZDDIFRUYFGPBGC-UHFFFAOYSA-N
Data: 3 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat)) | BDBM50126481 (2-[4-(1H-Benzoimidazol-4-yl)-piperazin-1-ylmethyl]...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 4.10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universidad Complutense Curated by ChEMBL | Assay Description Binding affinity of the compound towards 5-HT 1A receptor in rat cerebral cortex membranes using [3H]-8-OH-DPAT as radioligand | Bioorg Med Chem Lett 13: 1429-32 (2003) BindingDB Entry DOI: 10.7270/Q2BV7FZX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat)) | BDBM50126481 (2-[4-(1H-Benzoimidazol-4-yl)-piperazin-1-ylmethyl]...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 4.10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description In vitro inhibition of [3H]8-OH-DPAT binding to 5-hydroxytryptamine 1A receptor in rat cerebral cortex membranes | J Med Chem 48: 2548-2558 (2005) Article DOI: 10.1021/jm048999e BindingDB Entry DOI: 10.7270/Q23F4PNB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-1 Adrenergic Receptor/ adrenergic receptor/ adrenergic receptor (Rattus norvegicus (rat)-Rattus norvegicus (Rat)) | BDBM50126481 (2-[4-(1H-Benzoimidazol-4-yl)-piperazin-1-ylmethyl]...) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universidad Complutense Curated by ChEMBL | Assay Description Binding affinity towards Alpha-1 adrenergic receptor in rat cerebral cortex membranes using [3H]prazosin as radioligand | Bioorg Med Chem Lett 13: 1429-32 (2003) BindingDB Entry DOI: 10.7270/Q2BV7FZX | |||||||||||
More data for this Ligand-Target Pair |