BDBM50126494 2-(3-Amino-4-cyclobutylsulfamoyl-6-methyl-2-oxo-2H-pyridin-1-yl)-N-(6-amino-2-methyl-pyridin-3-ylmethyl)-acetamide::CHEMBL32931

SMILES: Cc1cc(c(N)c(=O)n1CC(=O)NCc1ccc(N)nc1C)S(=O)(=O)NC1CCC1

InChI Key: InChIKey=RAJYQBFEAGRQII-UHFFFAOYSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50126494   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prothrombin (Homo sapiens (Human))	BDBM50126494 (2-(3-Amino-4-cyclobutylsulfamoyl-6-methyl-2-oxo-2H...) Show SMILES Cc1cc(c(N)c(=O)n1CC(=O)NCc1ccc(N)nc1C)S(=O)(=O)NC1CCC1 Show InChI InChI=1S/C19H26N6O4S/c1-11-8-15(30(28,29)24-14-4-3-5-14)18(21)19(27)25(11)10-17(26)22-9-13-6-7-16(20)23-12(13)2/h6-8,14,24H,3-5,9-10,21H2,1-2H3,(H2,20,23)(H,22,26)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	1.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of human thrombin				Bioorg Med Chem Lett 13: 1441-4 (2003) BindingDB Entry DOI: 10.7270/Q2736Q8C
					More data for this Ligand-Target Pair
Trypsin-1 (Homo sapiens (Human))	BDBM50126494 (2-(3-Amino-4-cyclobutylsulfamoyl-6-methyl-2-oxo-2H...) Show SMILES Cc1cc(c(N)c(=O)n1CC(=O)NCc1ccc(N)nc1C)S(=O)(=O)NC1CCC1 Show InChI InChI=1S/C19H26N6O4S/c1-11-8-15(30(28,29)24-14-4-3-5-14)18(21)19(27)25(11)10-17(26)22-9-13-6-7-16(20)23-12(13)2/h6-8,14,24H,3-5,9-10,21H2,1-2H3,(H2,20,23)(H,22,26)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	1.10E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibitory activity of the compound against human trypsin				Bioorg Med Chem Lett 13: 1441-4 (2003) BindingDB Entry DOI: 10.7270/Q2736Q8C
					More data for this Ligand-Target Pair