BDBM50126536 (1-Hydroxy-2,5-dioxo-pyrrolidin-3-yl)-acetic acid::CHEMBL284271

SMILES: ON1C(=O)CC(CC(O)=O)C1=O

InChI Key: InChIKey=SQPSXVPPAZXZCA-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50126536   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Egl nine homolog 2 (Homo sapiens (Human))	BDBM50126536 ((1-Hydroxy-2,5-dioxo-pyrrolidin-3-yl)-acetic acid ...) Show SMILES ON1C(=O)CC(CC(O)=O)C1=O Show InChI InChI=1S/C6H7NO5/c8-4-1-3(2-5(9)10)6(11)7(4)12/h3,12H,1-2H2,(H,9,10)	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	PubMed	n/a	n/a	1.00E+6	n/a	n/a	n/a	n/a	n/a	n/a
Oxford Centre for Molecular Sciences Curated by ChEMBL					Assay Description Inhibitory activity of the compound against purified fusion of maltose binding with PHD1 as enzyme and (HIF) human prolyl hydroxylases as substrate				Bioorg Med Chem Lett 13: 1451-4 (2003) BindingDB Entry DOI: 10.7270/Q2ZP45HH
					More data for this Ligand-Target Pair