BDBM50126579 2-[3-(4-Carbamimidoyl-phenyl)-ureido]-N-[(S)-1-(3-methoxy-phenyl)-ethyl]-acetamide::2-[3-(4-Carbamimidoyl-phenyl)-ureido]-N-[1-((S)-3-methoxy-phenyl)-ethyl]-acetamide::CHEMBL34887
SMILES: COc1cccc(c1)[C@H](C)NC(=O)CNC(=O)Nc1ccc(cc1)C(N)=N
InChI Key: InChIKey=GLFJKCDLOVHCTQ-LBPRGKRZSA-N
Data: 6 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Coagulation factor VII (Homo sapiens (Human)) | BDBM50126579 (2-[3-(4-Carbamimidoyl-phenyl)-ureido]-N-[(S)-1-(3-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | 35 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Aventis Pharma Deutschland GmbH Curated by ChEMBL | Assay Description In vitro inhibitory activity against coagulation factor VII (fVIIa) | Bioorg Med Chem Lett 13: 1463-7 (2003) BindingDB Entry DOI: 10.7270/Q2Q52P1B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Coagulation factor VII (Homo sapiens (Human)) | BDBM50126579 (2-[3-(4-Carbamimidoyl-phenyl)-ureido]-N-[(S)-1-(3-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 35 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Aventis Pharma Deutschland GmbH Curated by ChEMBL | Assay Description In vitro inhibition of human coagulation factor VIIa | Bioorg Med Chem Lett 14: 3715-20 (2004) Article DOI: 10.1016/j.bmcl.2004.05.006 BindingDB Entry DOI: 10.7270/Q2PG1R6T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Coagulation factor X (Homo sapiens (Human)) | BDBM50126579 (2-[3-(4-Carbamimidoyl-phenyl)-ureido]-N-[(S)-1-(3-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Aventis Pharma Deutschland GmbH Curated by ChEMBL | Assay Description In vitro inhibition of coagulation factor X | Bioorg Med Chem Lett 14: 3715-20 (2004) Article DOI: 10.1016/j.bmcl.2004.05.006 BindingDB Entry DOI: 10.7270/Q2PG1R6T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Coagulation factor X (Homo sapiens (Human)) | BDBM50126579 (2-[3-(4-Carbamimidoyl-phenyl)-ureido]-N-[(S)-1-(3-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Aventis Pharma Deutschland GmbH Curated by ChEMBL | Assay Description In vitro inhibitory activity against zymogen coagulation factor (fXa) | Bioorg Med Chem Lett 13: 1463-7 (2003) BindingDB Entry DOI: 10.7270/Q2Q52P1B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prothrombin (Homo sapiens (Human)) | BDBM50126579 (2-[3-(4-Carbamimidoyl-phenyl)-ureido]-N-[(S)-1-(3-...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | 1.82E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Aventis Pharma Deutschland GmbH Curated by ChEMBL | Assay Description In vitro inhibitory activity against thrombin | Bioorg Med Chem Lett 13: 1463-7 (2003) BindingDB Entry DOI: 10.7270/Q2Q52P1B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prothrombin (Homo sapiens (Human)) | BDBM50126579 (2-[3-(4-Carbamimidoyl-phenyl)-ureido]-N-[(S)-1-(3-...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 1.82E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Aventis Pharma Deutschland GmbH Curated by ChEMBL | Assay Description In vitro inhibition of thrombin | Bioorg Med Chem Lett 14: 3715-20 (2004) Article DOI: 10.1016/j.bmcl.2004.05.006 BindingDB Entry DOI: 10.7270/Q2PG1R6T | |||||||||||
More data for this Ligand-Target Pair |