BDBM50126622 4-(N-benzyl-4-methoxyphenylsulfonamido)-N-hydroxy-8-(trifluoromethyl)quinoline-3-carboxamide::4-[Benzyl-(4-methoxy-benzenesulfonyl)-amino]-8-trifluoromethyl-quinoline-3-carboxylic acid hydroxyamide::CHEMBL34411

SMILES: COc1ccc(cc1)S(=O)(=O)N(Cc1ccccc1)c1c(cnc2c(cccc12)C(F)(F)F)C(=O)NO

InChI Key: InChIKey=AXTUTMYETKQSJS-UHFFFAOYSA-N

Data: 5 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50126622   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Matrix metalloproteinase-9 (Homo sapiens (Human))	BDBM50126622 (4-(N-benzyl-4-methoxyphenylsulfonamido)-N-hydroxy-...) Show SMILES COc1ccc(cc1)S(=O)(=O)N(Cc1ccccc1)c1c(cnc2c(cccc12)C(F)(F)F)C(=O)NO Show InChI InChI=1S/C25H20F3N3O5S/c1-36-17-10-12-18(13-11-17)37(34,35)31(15-16-6-3-2-4-7-16)23-19-8-5-9-21(25(26,27)28)22(19)29-14-20(23)24(32)30-33/h2-14,33H,15H2,1H3,(H,30,32)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth-Ayerst Research Curated by ChEMBL					Assay Description Inhibitory activity against matrix metalloproteinase 9 (MMP-9).				Bioorg Med Chem Lett 13: 1487-90 (2003) BindingDB Entry DOI: 10.7270/Q29W0DW0
					More data for this Ligand-Target Pair
Disintegrin and metalloproteinase domain-containing protein 17 (Homo sapiens (Human))	BDBM50126622 (4-(N-benzyl-4-methoxyphenylsulfonamido)-N-hydroxy-...) Show SMILES COc1ccc(cc1)S(=O)(=O)N(Cc1ccccc1)c1c(cnc2c(cccc12)C(F)(F)F)C(=O)NO Show InChI InChI=1S/C25H20F3N3O5S/c1-36-17-10-12-18(13-11-17)37(34,35)31(15-16-6-3-2-4-7-16)23-19-8-5-9-21(25(26,27)28)22(19)29-14-20(23)24(32)30-33/h2-14,33H,15H2,1H3,(H,30,32)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	190	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth-Ayerst Research Curated by ChEMBL					Assay Description Inhibitory activity against TACE.				Bioorg Med Chem Lett 13: 1487-90 (2003) BindingDB Entry DOI: 10.7270/Q29W0DW0
					More data for this Ligand-Target Pair
Interstitial collagenase (Homo sapiens (Human))	BDBM50126622 (4-(N-benzyl-4-methoxyphenylsulfonamido)-N-hydroxy-...) Show SMILES COc1ccc(cc1)S(=O)(=O)N(Cc1ccccc1)c1c(cnc2c(cccc12)C(F)(F)F)C(=O)NO Show InChI InChI=1S/C25H20F3N3O5S/c1-36-17-10-12-18(13-11-17)37(34,35)31(15-16-6-3-2-4-7-16)23-19-8-5-9-21(25(26,27)28)22(19)29-14-20(23)24(32)30-33/h2-14,33H,15H2,1H3,(H,30,32)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	933	n/a	n/a	n/a	n/a	n/a	n/a
Pomona College Curated by ChEMBL					Assay Description Inhibition of MMP1				Bioorg Med Chem 15: 2223-68 (2007) Article DOI: 10.1016/j.bmc.2007.01.011 BindingDB Entry DOI: 10.7270/Q2571DBD
					More data for this Ligand-Target Pair
Collagenase 3 (Homo sapiens (Human))	BDBM50126622 (4-(N-benzyl-4-methoxyphenylsulfonamido)-N-hydroxy-...) Show SMILES COc1ccc(cc1)S(=O)(=O)N(Cc1ccccc1)c1c(cnc2c(cccc12)C(F)(F)F)C(=O)NO Show InChI InChI=1S/C25H20F3N3O5S/c1-36-17-10-12-18(13-11-17)37(34,35)31(15-16-6-3-2-4-7-16)23-19-8-5-9-21(25(26,27)28)22(19)29-14-20(23)24(32)30-33/h2-14,33H,15H2,1H3,(H,30,32)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth-Ayerst Research Curated by ChEMBL					Assay Description Inhibitory activity against matrix metalloproteinase 13 (MMP-13).				Bioorg Med Chem Lett 13: 1487-90 (2003) BindingDB Entry DOI: 10.7270/Q29W0DW0
					More data for this Ligand-Target Pair
Interstitial collagenase (Homo sapiens (Human))	BDBM50126622 (4-(N-benzyl-4-methoxyphenylsulfonamido)-N-hydroxy-...) Show SMILES COc1ccc(cc1)S(=O)(=O)N(Cc1ccccc1)c1c(cnc2c(cccc12)C(F)(F)F)C(=O)NO Show InChI InChI=1S/C25H20F3N3O5S/c1-36-17-10-12-18(13-11-17)37(34,35)31(15-16-6-3-2-4-7-16)23-19-8-5-9-21(25(26,27)28)22(19)29-14-20(23)24(32)30-33/h2-14,33H,15H2,1H3,(H,30,32)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	933	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth-Ayerst Research Curated by ChEMBL					Assay Description Inhibitory activity against matrix metalloproteinase 1 (MMP-1).				Bioorg Med Chem Lett 13: 1487-90 (2003) BindingDB Entry DOI: 10.7270/Q29W0DW0
					More data for this Ligand-Target Pair