BDBM50126652 2-METHANESULFONYL-BENZENESULFONIC ACID 3-METHYL-5-((1-AMIDINOAMINOOXYMETHYL-CYCLOPROPYL)METHYLOXY)-PHENYLESTER::3-({1-[({[(Z)-amino(imino)methyl]amino}oxy)methyl]cyclopropyl}methoxy)-5-methylphenyl 2-(methylsulfonyl)benzenesulfonate::CHEMBL36040
SMILES: Cc1cc(OCC2(CONC(N)=N)CC2)cc(OS(=O)(=O)c2ccccc2S(C)(=O)=O)c1
InChI Key: InChIKey=FXPLUZROHGTSCH-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
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Prothrombin (Homo sapiens (Human)) | BDBM50126652 (2-METHANESULFONYL-BENZENESULFONIC ACID 3-METHYL-5-...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL MMDB PC cid PC sid PDB UniChem Patents Similars | PDB PubMed | 7.70 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
3-Dimensional Pharmaceuticals, Inc. Curated by ChEMBL | Assay Description Inhibitory activity of the compound was tested against alpha-human thrombin | Bioorg Med Chem Lett 13: 1495-8 (2003) BindingDB Entry DOI: 10.7270/Q2668CJ9 | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) |