BDBM50126656 CHEMBL263595::Compound [Gly2]Venorphin
SMILES: CC(C)C[C@H](NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)CNC(=O)[C@H](Cc1ccc(O)cc1)NC(C)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCCN)C(N)=O
InChI Key: InChIKey=LEOOYGZIPCAMDR-UAJYPUKQSA-N
Data: 3 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Kappa-type opioid receptor (Cavia porcellus (domestic guinea pig)) | BDBM50126656 (CHEMBL263595 | Compound [Gly2]Venorphin) | PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 8.40 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Maryland Curated by ChEMBL | Assay Description Binding affinity of the compound towards Opioid receptor kappa 1 using [3H]-Diprenorphine as radioligand in Chinese hamster ovary cells expressing cl... | J Med Chem 46: 1279-82 (2003) Article DOI: 10.1021/jm0256023 BindingDB Entry DOI: 10.7270/Q22F7MTK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mu-type opioid receptor (Homo sapiens (Human)) | BDBM50126656 (CHEMBL263595 | Compound [Gly2]Venorphin) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 339 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Maryland Curated by ChEMBL | Assay Description Binding affinity of the compound towards Opioid receptor mu 1 using [3H]-DAMGO as radioligand in Chinese hamster ovary cells expressing cloned opioid... | J Med Chem 46: 1279-82 (2003) Article DOI: 10.1021/jm0256023 BindingDB Entry DOI: 10.7270/Q22F7MTK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Opioid receptors; mu & delta (Rattus norvegicus (rat)) | BDBM50126656 (CHEMBL263595 | Compound [Gly2]Venorphin) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Maryland Curated by ChEMBL | Assay Description Binding affinity of the compound towards Opioid receptor delta 1 using [3H]-DPDPE as radioligand in Chinese hamster ovary cells expressing cloned opi... | J Med Chem 46: 1279-82 (2003) Article DOI: 10.1021/jm0256023 BindingDB Entry DOI: 10.7270/Q22F7MTK | |||||||||||
More data for this Ligand-Target Pair |