BDBM50126850 CHEMBL3628818

SMILES: Clc1ccc(Nc2ncc3CSc4cc(Cl)ccc4-c3n2)cc1

InChI Key: InChIKey=KRPKPDYONWEWGV-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50126850   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50126850 (CHEMBL3628818) Show SMILES Clc1ccc(Nc2ncc3CSc4cc(Cl)ccc4-c3n2)cc1 Show InChI InChI=1S/C17H11Cl2N3S/c18-11-1-4-13(5-2-11)21-17-20-8-10-9-23-15-7-12(19)3-6-14(15)16(10)22-17/h1-8H,9H2,(H,20,21,22)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	5.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Pisa Curated by ChEMBL					Assay Description Inhibition of human KDR incubated for 50 mins by omnia tyr peptide 8 substrate based fluorescence assay				Eur J Med Chem 103: 29-43 (2015) BindingDB Entry DOI: 10.7270/Q2G162MG
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50126850 (CHEMBL3628818) Show SMILES Clc1ccc(Nc2ncc3CSc4cc(Cl)ccc4-c3n2)cc1 Show InChI InChI=1S/C17H11Cl2N3S/c18-11-1-4-13(5-2-11)21-17-20-8-10-9-23-15-7-12(19)3-6-14(15)16(10)22-17/h1-8H,9H2,(H,20,21,22)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	4.57E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Pisa Curated by ChEMBL					Assay Description Inhibition of EGFR (unknown origin) using omnia tyr peptide 7 substrate by fluorescence assay				Eur J Med Chem 103: 29-43 (2015) BindingDB Entry DOI: 10.7270/Q2G162MG
					More data for this Ligand-Target Pair