BDBM50126852 CHEMBL3628817

SMILES: COc1ccc(Nc2ncc3CSc4cc(Cl)ccc4-c3n2)cc1

InChI Key: InChIKey=YBRIVXKFUFUDFB-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50126852   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50126852 (CHEMBL3628817) Show SMILES COc1ccc(Nc2ncc3CSc4cc(Cl)ccc4-c3n2)cc1 Show InChI InChI=1S/C18H14ClN3OS/c1-23-14-5-3-13(4-6-14)21-18-20-9-11-10-24-16-8-12(19)2-7-15(16)17(11)22-18/h2-9H,10H2,1H3,(H,20,21,22)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.16E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Pisa Curated by ChEMBL					Assay Description Inhibition of EGFR (unknown origin) using omnia tyr peptide 7 substrate by fluorescence assay				Eur J Med Chem 103: 29-43 (2015) BindingDB Entry DOI: 10.7270/Q2G162MG
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50126852 (CHEMBL3628817) Show SMILES COc1ccc(Nc2ncc3CSc4cc(Cl)ccc4-c3n2)cc1 Show InChI InChI=1S/C18H14ClN3OS/c1-23-14-5-3-13(4-6-14)21-18-20-9-11-10-24-16-8-12(19)2-7-15(16)17(11)22-18/h2-9H,10H2,1H3,(H,20,21,22)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Pisa Curated by ChEMBL					Assay Description Inhibition of human KDR incubated for 50 mins by omnia tyr peptide 8 substrate based fluorescence assay				Eur J Med Chem 103: 29-43 (2015) BindingDB Entry DOI: 10.7270/Q2G162MG
					More data for this Ligand-Target Pair