BDBM50126853 CHEMBL3628815

SMILES: COc1ccc-2c(SCc3cnc(Nc4ccc(Cl)cc4)nc-23)c1

InChI Key: InChIKey=HQIGRNOEKLAIHC-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50126853   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50126853 (CHEMBL3628815) Show SMILES COc1ccc-2c(SCc3cnc(Nc4ccc(Cl)cc4)nc-23)c1 Show InChI InChI=1S/C18H14ClN3OS/c1-23-14-6-7-15-16(8-14)24-10-11-9-20-18(22-17(11)15)21-13-4-2-12(19)3-5-13/h2-9H,10H2,1H3,(H,20,21,22)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Pisa Curated by ChEMBL					Assay Description Inhibition of human KDR incubated for 50 mins by omnia tyr peptide 8 substrate based fluorescence assay				Eur J Med Chem 103: 29-43 (2015) BindingDB Entry DOI: 10.7270/Q2G162MG
					More data for this Ligand-Target Pair