BDBM50126884 1-[4-(4-Piperidin-1-ylmethyl-benzyloxy)-phenyl]-ethanone; compound with oxalic acid::CHEMBL39603
SMILES: CC(=O)c1ccc(OCc2ccc(CN3CCCCC3)cc2)cc1
InChI Key: InChIKey=ARBBIPRORVNXCC-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
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Histamine H3 receptor (Homo sapiens (Human)) | BDBM50126884 (1-[4-(4-Piperidin-1-ylmethyl-benzyloxy)-phenyl]-et...) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 84 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Freie Universit£t Berlin Curated by ChEMBL | Assay Description Displacement of [125I]iodoproxyfan from human histamine H3 receptor expressing CHO cells | J Med Chem 46: 1523-30 (2003) Article DOI: 10.1021/jm021084k BindingDB Entry DOI: 10.7270/Q2C24X5N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Histamine H1 receptor (Cavia porcellus (domestic guinea pig)) | BDBM50126884 (1-[4-(4-Piperidin-1-ylmethyl-benzyloxy)-phenyl]-et...) | UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | 4.57E+3 | n/a | n/a | n/a | n/a | n/a |
Freie Universit£t Berlin Curated by ChEMBL | Assay Description Potency at histamine H1 receptor subtype, was tested on guinea pig right ileum | J Med Chem 46: 1523-30 (2003) Article DOI: 10.1021/jm021084k BindingDB Entry DOI: 10.7270/Q2C24X5N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
HRH3 (GUINEA PIG) | BDBM50126884 (1-[4-(4-Piperidin-1-ylmethyl-benzyloxy)-phenyl]-et...) | UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | 61.7 | n/a | n/a | n/a | n/a | n/a |
Freie Universit£t Berlin Curated by ChEMBL | Assay Description Potency at histamine H3 receptor subtype, was tested on guinea pig right ileum | J Med Chem 46: 1523-30 (2003) Article DOI: 10.1021/jm021084k BindingDB Entry DOI: 10.7270/Q2C24X5N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Histamine N-methyltransferase (Rattus norvegicus) | BDBM50126884 (1-[4-(4-Piperidin-1-ylmethyl-benzyloxy)-phenyl]-et...) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.04E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Freie Universit£t Berlin Curated by ChEMBL | Assay Description Compound was tested against histamine N-methyl-transferase in rat brain [EC 2.1.1.8](relative weak affinity on rat enzyme) | J Med Chem 46: 1523-30 (2003) Article DOI: 10.1021/jm021084k BindingDB Entry DOI: 10.7270/Q2C24X5N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Histamine H2 receptor (Cavia porcellus (domestic guinea pig)) | BDBM50126884 (1-[4-(4-Piperidin-1-ylmethyl-benzyloxy)-phenyl]-et...) | UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | 1.02E+4 | n/a | n/a | n/a | n/a | n/a |
Freie Universit£t Berlin Curated by ChEMBL | Assay Description Potency at histamine H2 receptor subtype, was tested on guinea pig right atrium | J Med Chem 46: 1523-30 (2003) Article DOI: 10.1021/jm021084k BindingDB Entry DOI: 10.7270/Q2C24X5N | |||||||||||
More data for this Ligand-Target Pair |