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BDBM50126891 1-[4-(4-Chloro-3-fluoro-phenoxymethyl)-benzyl]-piperidine; compound with oxalic acid::CHEMBL39956

SMILES: Fc1cc(OCc2ccc(CN3CCCCC3)cc2)ccc1Cl

InChI Key: InChIKey=QURHGLMOAFXJDP-UHFFFAOYSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50126891   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Histamine receptor (H3)


(Homo sapiens (Human))
BDBM50126891
PNG
(1-[4-(4-Chloro-3-fluoro-phenoxymethyl)-benzyl]-pip...)
Show SMILES Fc1cc(OCc2ccc(CN3CCCCC3)cc2)ccc1Cl
Show InChI InChI=1S/C19H21ClFNO/c20-18-9-8-17(12-19(18)21)23-14-16-6-4-15(5-7-16)13-22-10-2-1-3-11-22/h4-9,12H,1-3,10-11,13-14H2
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PC cid
PC sid
UniChem
Article
PubMed
95n/an/an/an/an/an/an/an/a



Freie Universit£t Berlin

Curated by ChEMBL


Assay Description
Displacement of [125I]iodoproxyfan from human histamine H3 receptor expressing CHO cells


J Med Chem 46: 1523-30 (2003)


Article DOI: 10.1021/jm021084k
BindingDB Entry DOI: 10.7270/Q2C24X5N
More data for this
Ligand-Target Pair