BDBM50126899 1-[4-(4-Piperidin-1-ylmethyl-benzyloxy)-phenyl]-ethanone O-methyl-oxime; compound with oxalic acid::CHEMBL35869

SMILES: CO\N=C(/C)c1ccc(OCc2ccc(CN3CCCCC3)cc2)cc1

InChI Key: InChIKey=UEFRXFKPOVSXIY-PTGBLXJZSA-N

Data: 1 KI  3 Kd

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50126899   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histamine H3 receptor (Homo sapiens (Human))	BDBM50126899 (1-[4-(4-Piperidin-1-ylmethyl-benzyloxy)-phenyl]-et...) Show SMILES CO\N=C(/C)c1ccc(OCc2ccc(CN3CCCCC3)cc2)cc1 Show InChI InChI=1S/C22H28N2O2/c1-18(23-25-2)21-10-12-22(13-11-21)26-17-20-8-6-19(7-9-20)16-24-14-4-3-5-15-24/h6-13H,3-5,14-17H2,1-2H3/b23-18+	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	129	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Freie Universit£t Berlin Curated by ChEMBL					Assay Description Displacement of [125I]iodoproxyfan from human histamine H3 receptor expressing CHO cells				J Med Chem 46: 1523-30 (2003) Article DOI: 10.1021/jm021084k BindingDB Entry DOI: 10.7270/Q2C24X5N
					More data for this Ligand-Target Pair
Histamine H1 receptor (Cavia porcellus (domestic guinea pig))	BDBM50126899 (1-[4-(4-Piperidin-1-ylmethyl-benzyloxy)-phenyl]-et...) Show SMILES CO\N=C(/C)c1ccc(OCc2ccc(CN3CCCCC3)cc2)cc1 Show InChI InChI=1S/C22H28N2O2/c1-18(23-25-2)21-10-12-22(13-11-21)26-17-20-8-6-19(7-9-20)16-24-14-4-3-5-15-24/h6-13H,3-5,14-17H2,1-2H3/b23-18+	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	3.47E+3	n/a	n/a	n/a	n/a	n/a
Freie Universit£t Berlin Curated by ChEMBL					Assay Description Potency at histamine H1 receptor subtype, was tested on guinea pig right ileum				J Med Chem 46: 1523-30 (2003) Article DOI: 10.1021/jm021084k BindingDB Entry DOI: 10.7270/Q2C24X5N
					More data for this Ligand-Target Pair
Histamine H2 receptor (Cavia porcellus (domestic guinea pig))	BDBM50126899 (1-[4-(4-Piperidin-1-ylmethyl-benzyloxy)-phenyl]-et...) Show SMILES CO\N=C(/C)c1ccc(OCc2ccc(CN3CCCCC3)cc2)cc1 Show InChI InChI=1S/C22H28N2O2/c1-18(23-25-2)21-10-12-22(13-11-21)26-17-20-8-6-19(7-9-20)16-24-14-4-3-5-15-24/h6-13H,3-5,14-17H2,1-2H3/b23-18+	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	3.98E+3	n/a	n/a	n/a	n/a	n/a
Freie Universit£t Berlin Curated by ChEMBL					Assay Description Potency at histamine H2 receptor subtype, was tested on guinea pig right atrium				J Med Chem 46: 1523-30 (2003) Article DOI: 10.1021/jm021084k BindingDB Entry DOI: 10.7270/Q2C24X5N
					More data for this Ligand-Target Pair
HRH3 (GUINEA PIG)	BDBM50126899 (1-[4-(4-Piperidin-1-ylmethyl-benzyloxy)-phenyl]-et...) Show SMILES CO\N=C(/C)c1ccc(OCc2ccc(CN3CCCCC3)cc2)cc1 Show InChI InChI=1S/C22H28N2O2/c1-18(23-25-2)21-10-12-22(13-11-21)26-17-20-8-6-19(7-9-20)16-24-14-4-3-5-15-24/h6-13H,3-5,14-17H2,1-2H3/b23-18+	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	288	n/a	n/a	n/a	n/a	n/a
Freie Universit£t Berlin Curated by ChEMBL					Assay Description Potency at histamine H3 receptor subtype, was tested on guinea pig right ileum				J Med Chem 46: 1523-30 (2003) Article DOI: 10.1021/jm021084k BindingDB Entry DOI: 10.7270/Q2C24X5N
					More data for this Ligand-Target Pair