BDBM50126927 CHEMBL3628836

SMILES: Cc1ncn(n1)-c1cc(Cl)c(C(=O)N[C@]2(CO)CCc3nn4cc(C)ccc4c3C2)c(Cl)c1

InChI Key: InChIKey=IHHHNAHSZOZUGR-HSZRJFAPSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50126927   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Coagulation factor IX (Homo sapiens (Human))	BDBM50126927 (CHEMBL3628836) Show SMILES Cc1ncn(n1)-c1cc(Cl)c(C(=O)N[C@]2(CO)CCc3nn4cc(C)ccc4c3C2)c(Cl)c1 |r| Show InChI InChI=1S/C23H22Cl2N6O2/c1-13-3-4-20-16-9-23(11-32,6-5-19(16)29-30(20)10-13)27-22(33)21-17(24)7-15(8-18(21)25)31-12-26-14(2)28-31/h3-4,7-8,10,12,32H,5-6,9,11H2,1-2H3,(H,27,33)/t23-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	14	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of human F9a using CH3SO2-D-CHG-Gly-Arg-AFC.AcOH as substrate by fluorescence assay				Bioorg Med Chem Lett 25: 5437-43 (2015) BindingDB Entry DOI: 10.7270/Q2B859X6
					More data for this Ligand-Target Pair
Coagulation factor X (Homo sapiens (Human))	BDBM50126927 (CHEMBL3628836) Show SMILES Cc1ncn(n1)-c1cc(Cl)c(C(=O)N[C@]2(CO)CCc3nn4cc(C)ccc4c3C2)c(Cl)c1 |r| Show InChI InChI=1S/C23H22Cl2N6O2/c1-13-3-4-20-16-9-23(11-32,6-5-19(16)29-30(20)10-13)27-22(33)21-17(24)7-15(8-18(21)25)31-12-26-14(2)28-31/h3-4,7-8,10,12,32H,5-6,9,11H2,1-2H3,(H,27,33)/t23-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	1.01E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of human F10a using CH3SO2-D-CHG-Gly-Arg-AFC.AcOH as substrate by fluorescence assay				Bioorg Med Chem Lett 25: 5437-43 (2015) BindingDB Entry DOI: 10.7270/Q2B859X6
					More data for this Ligand-Target Pair