BDBM50126950 CHEMBL3628955

SMILES: Cc1ccc2c3C[C@@](C)(CCc3nn2c1)NC(=O)c1ccc(cc1Cl)-n1cnc2cc(ccc12)C(O)=O

InChI Key: InChIKey=HHIOZKIZFWMNIY-MUUNZHRXSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50126950   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Coagulation factor IX (Homo sapiens (Human))	BDBM50126950 (CHEMBL3628955) Show SMILES Cc1ccc2c3C[C@@](C)(CCc3nn2c1)NC(=O)c1ccc(cc1Cl)-n1cnc2cc(ccc12)C(O)=O |r| Show InChI InChI=1S/C28H24ClN5O3/c1-16-3-7-24-20-13-28(2,10-9-22(20)32-34(24)14-16)31-26(35)19-6-5-18(12-21(19)29)33-15-30-23-11-17(27(36)37)4-8-25(23)33/h3-8,11-12,14-15H,9-10,13H2,1-2H3,(H,31,35)(H,36,37)/t28-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	11	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of human F9a using CH3SO2-D-CHG-Gly-Arg-AFC.AcOH as substrate by fluorescence assay				Bioorg Med Chem Lett 25: 5437-43 (2015) BindingDB Entry DOI: 10.7270/Q2B859X6
					More data for this Ligand-Target Pair
Coagulation factor X (Homo sapiens (Human))	BDBM50126950 (CHEMBL3628955) Show SMILES Cc1ccc2c3C[C@@](C)(CCc3nn2c1)NC(=O)c1ccc(cc1Cl)-n1cnc2cc(ccc12)C(O)=O |r| Show InChI InChI=1S/C28H24ClN5O3/c1-16-3-7-24-20-13-28(2,10-9-22(20)32-34(24)14-16)31-26(35)19-6-5-18(12-21(19)29)33-15-30-23-11-17(27(36)37)4-8-25(23)33/h3-8,11-12,14-15H,9-10,13H2,1-2H3,(H,31,35)(H,36,37)/t28-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	518	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of human F10a using CH3SO2-D-CHG-Gly-Arg-AFC.AcOH as substrate by fluorescence assay				Bioorg Med Chem Lett 25: 5437-43 (2015) BindingDB Entry DOI: 10.7270/Q2B859X6
					More data for this Ligand-Target Pair