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SMILES: Oc1ccc(cc1)-c1cnc2[nH]ccc2n1

InChI Key: InChIKey=OPCDTRLJCLTNPN-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50127027   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Mitogen-activated protein kinase 1


(Homo sapiens (Human))		BDBM50127027
PNG
(CHEMBL3628255)
Show SMILES Oc1ccc(cc1)-c1cnc2[nH]ccc2n1
Show InChI InChI=1S/C12H9N3O/c16-9-3-1-8(2-4-9)11-7-14-12-10(15-11)5-6-13-12/h1-7,16H,(H,13,14)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

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PC cid
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Similars
PubMed
n/an/a 1.24E+4n/an/an/an/an/an/a



Genentech

Curated by ChEMBL


Assay Description
Inhibition of ERK2 (unknown origin) using 5FAM-IPTSPITTTYFFFKKK as substrate after 1 hr by LC3K assay

Bioorg Med Chem Lett 25: 4728-32 (2015)


BindingDB Entry DOI: 10.7270/Q2TB18QM
More data for this
Ligand-Target Pair