BDBM50127085 CHEMBL3628373

SMILES: Clc1ccc(cn1)-c1c[nH]c2ncc(nc12)-c1ccncc1

InChI Key: InChIKey=NZTXIELVEWGKJA-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50127085   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase 1 (Homo sapiens (Human))	BDBM50127085 (CHEMBL3628373) Show SMILES Clc1ccc(cn1)-c1c[nH]c2ncc(nc12)-c1ccncc1 Show InChI InChI=1S/C16H10ClN5/c17-14-2-1-11(7-19-14)12-8-20-16-15(12)22-13(9-21-16)10-3-5-18-6-4-10/h1-9H,(H,20,21)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	182	n/a	n/a	n/a	n/a	n/a	n/a
Genentech Curated by ChEMBL					Assay Description Inhibition of ERK2 (unknown origin) using 5FAM-IPTSPITTTYFFFKKK as substrate after 1 hr by LC3K assay				Bioorg Med Chem Lett 25: 4728-32 (2015) BindingDB Entry DOI: 10.7270/Q2TB18QM
					More data for this Ligand-Target Pair