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SMILES: C(Cn1cc(cn1)-c1c[nH]c2ncc(nc12)-c1ccncc1)N1CCOCC1

InChI Key: InChIKey=JBYABIYRPIXQPV-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50127092   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Mitogen-activated protein kinase 1


(Homo sapiens (Human))		BDBM50127092
PNG
(CHEMBL3628381)
Show SMILES C(Cn1cc(cn1)-c1c[nH]c2ncc(nc12)-c1ccncc1)N1CCOCC1
Show InChI InChI=1S/C20H21N7O/c1-3-21-4-2-15(1)18-13-23-20-19(25-18)17(12-22-20)16-11-24-27(14-16)6-5-26-7-9-28-10-8-26/h1-4,11-14H,5-10H2,(H,22,23)
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MMDB

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KEGG

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n/an/a 416n/an/an/an/an/an/a



Genentech

Curated by ChEMBL


Assay Description
Inhibition of ERK2 (unknown origin) using 5FAM-IPTSPITTTYFFFKKK as substrate after 1 hr by LC3K assay

Bioorg Med Chem Lett 25: 4728-32 (2015)


BindingDB Entry DOI: 10.7270/Q2TB18QM
More data for this
Ligand-Target Pair