BDBM50127220 CHEMBL37495::{4-[4-Methyl-2-(4-trifluoromethyl-phenyl)-oxazol-5-ylmethylsulfanyl]-phenoxy}-acetic acid

SMILES: Cc1nc(oc1CSc1ccc(OCC(O)=O)cc1)-c1ccc(cc1)C(F)(F)F

InChI Key: InChIKey=JWWDUIBPFIEOPE-UHFFFAOYSA-N

Data: 1 IC50  2 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50127220   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Peroxisome proliferator-activated receptor delta (Homo sapiens (Human))	BDBM50127220 (CHEMBL37495 | {4-[4-Methyl-2-(4-trifluoromethyl-ph...) Show SMILES Cc1nc(oc1CSc1ccc(OCC(O)=O)cc1)-c1ccc(cc1)C(F)(F)F Show InChI InChI=1S/C20H16F3NO4S/c1-12-17(11-29-16-8-6-15(7-9-16)27-10-18(25)26)28-19(24-12)13-2-4-14(5-3-13)20(21,22)23/h2-9H,10-11H2,1H3,(H,25,26)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	90	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Binding affinity for human PPAR delta receptor				Bioorg Med Chem Lett 13: 1517-21 (2003) BindingDB Entry DOI: 10.7270/Q2VQ322G
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor (Homo sapiens (Human))	BDBM50127220 (CHEMBL37495 | {4-[4-Methyl-2-(4-trifluoromethyl-ph...) Show SMILES Cc1nc(oc1CSc1ccc(OCC(O)=O)cc1)-c1ccc(cc1)C(F)(F)F Show InChI InChI=1S/C20H16F3NO4S/c1-12-17(11-29-16-8-6-15(7-9-16)27-10-18(25)26)28-19(24-12)13-2-4-14(5-3-13)20(21,22)23/h2-9H,10-11H2,1H3,(H,25,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	n/a	n/a	6.40E+3	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Maximum transcriptional activation of human PPAR gamma receptor				Bioorg Med Chem Lett 13: 1517-21 (2003) BindingDB Entry DOI: 10.7270/Q2VQ322G
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor delta (Homo sapiens (Human))	BDBM50127220 (CHEMBL37495 | {4-[4-Methyl-2-(4-trifluoromethyl-ph...) Show SMILES Cc1nc(oc1CSc1ccc(OCC(O)=O)cc1)-c1ccc(cc1)C(F)(F)F Show InChI InChI=1S/C20H16F3NO4S/c1-12-17(11-29-16-8-6-15(7-9-16)27-10-18(25)26)28-19(24-12)13-2-4-14(5-3-13)20(21,22)23/h2-9H,10-11H2,1H3,(H,25,26)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	n/a	n/a	420	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Maximum transcriptional activation of human PPAR delta receptor				Bioorg Med Chem Lett 13: 1517-21 (2003) BindingDB Entry DOI: 10.7270/Q2VQ322G
					More data for this Ligand-Target Pair