BDBM50127280 5-Bromo-1-ethyl-7-[(4-fluoro-phenyl)-imidazol-1-yl-methyl]-2,3-dihydro-1H-indole::CHEMBL287950

SMILES: CCN1CCc2cc(Br)cc(C(c3ccc(F)cc3)n3ccnc3)c12

InChI Key: InChIKey=PLODWZXPMXDIRZ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50127280   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cytochrome P450 19A1 (Homo sapiens (Human))	BDBM50127280 (5-Bromo-1-ethyl-7-[(4-fluoro-phenyl)-imidazol-1-yl...) Show SMILES CCN1CCc2cc(Br)cc(C(c3ccc(F)cc3)n3ccnc3)c12 Show InChI InChI=1S/C20H19BrFN3/c1-2-24-9-7-15-11-16(21)12-18(20(15)24)19(25-10-8-23-13-25)14-3-5-17(22)6-4-14/h3-6,8,10-13,19H,2,7,9H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	90	n/a	n/a	n/a	n/a	n/a	n/a
UFR des Sciences Pharmaceutiques Curated by ChEMBL					Assay Description Inhibition of cytochrome P450 19A1 of human placental microsomes with [1beta,2beta-3H]testosterone				Bioorg Med Chem Lett 13: 1553-5 (2003) BindingDB Entry DOI: 10.7270/Q2GH9HB7
					More data for this Ligand-Target Pair