BDBM50127306 5-[(5-Cyano-3'-trifluoromethoxy-biphenyl-2-ylmethoxy)-(3-methyl-3H-imidazol-4-yl)-methyl]-pyridine-2-carbonitrile::CHEMBL38615

SMILES: Cn1cncc1C(OCc1ccc(cc1-c1cccc(OC(F)(F)F)c1)C#N)c1ccc(nc1)C#N

InChI Key: InChIKey=ZCOVCZOOFBWXSI-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50127306   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein Farnesyltransferase (PFT) (Bos taurus (bovine))	BDBM50127306 (5-[(5-Cyano-3'-trifluoromethoxy-biphenyl-2-ylmetho...) Show SMILES Cn1cncc1C(OCc1ccc(cc1-c1cccc(OC(F)(F)F)c1)C#N)c1ccc(nc1)C#N Show InChI InChI=1S/C26H18F3N5O2/c1-34-16-32-14-24(34)25(19-7-8-21(12-31)33-13-19)35-15-20-6-5-17(11-30)9-23(20)18-3-2-4-22(10-18)36-26(27,28)29/h2-10,13-14,16,25H,15H2,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	0.400	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of transfer of [3H]-FPP to biotin K-ras peptide (KKSKTKCVIM) catalyzed by bovine FTase				Bioorg Med Chem Lett 13: 1571-4 (2003) BindingDB Entry DOI: 10.7270/Q27080TK
					More data for this Ligand-Target Pair
Geranylgeranyl transferase type I (Homo sapiens (Human))	BDBM50127306 (5-[(5-Cyano-3'-trifluoromethoxy-biphenyl-2-ylmetho...) Show SMILES Cn1cncc1C(OCc1ccc(cc1-c1cccc(OC(F)(F)F)c1)C#N)c1ccc(nc1)C#N Show InChI InChI=1S/C26H18F3N5O2/c1-34-16-32-14-24(34)25(19-7-8-21(12-31)33-13-19)35-15-20-6-5-17(11-30)9-23(20)18-3-2-4-22(10-18)36-26(27,28)29/h2-10,13-14,16,25H,15H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	990	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of transfer of [3H]-FPP to biotin K-ras peptide (KKSKTKCVIM) catalyzed by bovine GGTase-I				Bioorg Med Chem Lett 13: 1571-4 (2003) BindingDB Entry DOI: 10.7270/Q27080TK
					More data for this Ligand-Target Pair