BDBM50127310 5-[(4-Cyano-phenyl)-(3-methyl-3H-imidazol-4-yl)-methoxymethyl]-6-naphthalen-2-yl-pyridine-2-carbonitrile::CHEMBL41515

SMILES: Cn1cncc1C(OCc1ccc(nc1-c1ccc2ccccc2c1)C#N)c1ccc(cc1)C#N

InChI Key: InChIKey=FHXPSLHVQVYMRI-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50127310   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein Farnesyltransferase (PFT) (Bos taurus (bovine))	BDBM50127310 (5-[(4-Cyano-phenyl)-(3-methyl-3H-imidazol-4-yl)-me...) Show SMILES Cn1cncc1C(OCc1ccc(nc1-c1ccc2ccccc2c1)C#N)c1ccc(cc1)C#N Show InChI InChI=1S/C29H21N5O/c1-34-19-32-17-27(34)29(22-8-6-20(15-30)7-9-22)35-18-25-12-13-26(16-31)33-28(25)24-11-10-21-4-2-3-5-23(21)14-24/h2-14,17,19,29H,18H2,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	0.160	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of [3H]-FPP transfer to biotin K-ras peptide (KKSKTKCVIM) catalyzed by bovine GGTase-I				Bioorg Med Chem Lett 13: 1571-4 (2003) BindingDB Entry DOI: 10.7270/Q27080TK
					More data for this Ligand-Target Pair
Geranylgeranyl transferase type I (Homo sapiens (Human))	BDBM50127310 (5-[(4-Cyano-phenyl)-(3-methyl-3H-imidazol-4-yl)-me...) Show SMILES Cn1cncc1C(OCc1ccc(nc1-c1ccc2ccccc2c1)C#N)c1ccc(cc1)C#N Show InChI InChI=1S/C29H21N5O/c1-34-19-32-17-27(34)29(22-8-6-20(15-30)7-9-22)35-18-25-12-13-26(16-31)33-28(25)24-11-10-21-4-2-3-5-23(21)14-24/h2-14,17,19,29H,18H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	5.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of transfer of [3H]-FPP to biotin K-ras peptide (KKSKTKCVIM) catalyzed by bovine GGTase-I				Bioorg Med Chem Lett 13: 1571-4 (2003) BindingDB Entry DOI: 10.7270/Q27080TK
					More data for this Ligand-Target Pair