BDBM50127468 2-[7-(3,5-Dimethyl-benzyloxy)-1,1-dioxo-1,3,4,5-tetrahydro-1lambda*6*-benzo[f][1,2,5]thiadiazepin-2-yl]-N-hydroxy-propionamide::CHEMBL293358

SMILES: C[C@@H](N1CCNc2cc(OCc3cc(C)cc(C)c3)ccc2S1(=O)=O)C(=O)NO

InChI Key: InChIKey=WPVBITLNIHHKGY-OAHLLOKOSA-N

Data: 4 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50127468   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
72 kDa type IV collagenase (Homo sapiens (Human))	BDBM50127468 (2-[7-(3,5-Dimethyl-benzyloxy)-1,1-dioxo-1,3,4,5-te...) Show SMILES C[C@@H](N1CCNc2cc(OCc3cc(C)cc(C)c3)ccc2S1(=O)=O)C(=O)NO Show InChI InChI=1S/C20H25N3O5S/c1-13-8-14(2)10-16(9-13)12-28-17-4-5-19-18(11-17)21-6-7-23(29(19,26)27)15(3)20(24)22-25/h4-5,8-11,15,21,25H,6-7,12H2,1-3H3,(H,22,24)/t15-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	136	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description In vitro inhibitory activity against broad spectrum matrix metalloprotease-2 (MMP-2)				J Med Chem 46: 1811-23 (2003) Article DOI: 10.1021/jm020475w BindingDB Entry DOI: 10.7270/Q2TQ60W7
					More data for this Ligand-Target Pair
Disintegrin and metalloproteinase domain-containing protein 17 (Homo sapiens (Human))	BDBM50127468 (2-[7-(3,5-Dimethyl-benzyloxy)-1,1-dioxo-1,3,4,5-te...) Show SMILES C[C@@H](N1CCNc2cc(OCc3cc(C)cc(C)c3)ccc2S1(=O)=O)C(=O)NO Show InChI InChI=1S/C20H25N3O5S/c1-13-8-14(2)10-16(9-13)12-28-17-4-5-19-18(11-17)21-6-7-23(29(19,26)27)15(3)20(24)22-25/h4-5,8-11,15,21,25H,6-7,12H2,1-3H3,(H,22,24)/t15-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	229	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description In vitro inhibitory activity against porcine tumor necrosis factor alpha converting enzyme (pTACE)				J Med Chem 46: 1811-23 (2003) Article DOI: 10.1021/jm020475w BindingDB Entry DOI: 10.7270/Q2TQ60W7
					More data for this Ligand-Target Pair
Matrix metalloproteinase-9 (Homo sapiens (Human))	BDBM50127468 (2-[7-(3,5-Dimethyl-benzyloxy)-1,1-dioxo-1,3,4,5-te...) Show SMILES C[C@@H](N1CCNc2cc(OCc3cc(C)cc(C)c3)ccc2S1(=O)=O)C(=O)NO Show InChI InChI=1S/C20H25N3O5S/c1-13-8-14(2)10-16(9-13)12-28-17-4-5-19-18(11-17)21-6-7-23(29(19,26)27)15(3)20(24)22-25/h4-5,8-11,15,21,25H,6-7,12H2,1-3H3,(H,22,24)/t15-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>2.13E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description In vitro inhibitory activity against broad spectrum matrix metalloprotease-9 (MMP-9)				J Med Chem 46: 1811-23 (2003) Article DOI: 10.1021/jm020475w BindingDB Entry DOI: 10.7270/Q2TQ60W7
					More data for this Ligand-Target Pair
Interstitial collagenase (Homo sapiens (Human))	BDBM50127468 (2-[7-(3,5-Dimethyl-benzyloxy)-1,1-dioxo-1,3,4,5-te...) Show SMILES C[C@@H](N1CCNc2cc(OCc3cc(C)cc(C)c3)ccc2S1(=O)=O)C(=O)NO Show InChI InChI=1S/C20H25N3O5S/c1-13-8-14(2)10-16(9-13)12-28-17-4-5-19-18(11-17)21-6-7-23(29(19,26)27)15(3)20(24)22-25/h4-5,8-11,15,21,25H,6-7,12H2,1-3H3,(H,22,24)/t15-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>4.95E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description In vitro inhibitory activity against broad spectrum matrix metalloprotease-1 (MMP-1)				J Med Chem 46: 1811-23 (2003) Article DOI: 10.1021/jm020475w BindingDB Entry DOI: 10.7270/Q2TQ60W7
					More data for this Ligand-Target Pair