BDBM50127477 2-(1,1-Dioxo-1,3,4,5-tetrahydro-1lambda*6*-benzo[f][1,2,5]thiadiazepin-2-yl)-N-hydroxy-propionamide::CHEMBL277972

SMILES: C[C@@H](N1CCNc2ccccc2S1(=O)=O)C(=O)NO

InChI Key: InChIKey=ZPDVGCNXBJNBDB-MRVPVSSYSA-N

Data: 4 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50127477   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
72 kDa type IV collagenase (Homo sapiens (Human))	BDBM50127477 (2-(1,1-Dioxo-1,3,4,5-tetrahydro-1lambda*6*-benzo[f...) Show SMILES C[C@@H](N1CCNc2ccccc2S1(=O)=O)C(=O)NO Show InChI InChI=1S/C11H15N3O4S/c1-8(11(15)13-16)14-7-6-12-9-4-2-3-5-10(9)19(14,17)18/h2-5,8,12,16H,6-7H2,1H3,(H,13,15)/t8-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	75	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description In vitro inhibitory activity against broad spectrum matrix metalloprotease-2 (MMP-2)				J Med Chem 46: 1811-23 (2003) Article DOI: 10.1021/jm020475w BindingDB Entry DOI: 10.7270/Q2TQ60W7
					More data for this Ligand-Target Pair
Disintegrin and metalloproteinase domain-containing protein 17 (Homo sapiens (Human))	BDBM50127477 (2-(1,1-Dioxo-1,3,4,5-tetrahydro-1lambda*6*-benzo[f...) Show SMILES C[C@@H](N1CCNc2ccccc2S1(=O)=O)C(=O)NO Show InChI InChI=1S/C11H15N3O4S/c1-8(11(15)13-16)14-7-6-12-9-4-2-3-5-10(9)19(14,17)18/h2-5,8,12,16H,6-7H2,1H3,(H,13,15)/t8-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	484	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description In vitro inhibitory activity against porcine tumor necrosis factor alpha converting enzyme (pTACE)				J Med Chem 46: 1811-23 (2003) Article DOI: 10.1021/jm020475w BindingDB Entry DOI: 10.7270/Q2TQ60W7
					More data for this Ligand-Target Pair
Matrix metalloproteinase-9 (Homo sapiens (Human))	BDBM50127477 (2-(1,1-Dioxo-1,3,4,5-tetrahydro-1lambda*6*-benzo[f...) Show SMILES C[C@@H](N1CCNc2ccccc2S1(=O)=O)C(=O)NO Show InChI InChI=1S/C11H15N3O4S/c1-8(11(15)13-16)14-7-6-12-9-4-2-3-5-10(9)19(14,17)18/h2-5,8,12,16H,6-7H2,1H3,(H,13,15)/t8-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	567	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description In vitro inhibitory activity against broad spectrum matrix metalloprotease-9 (MMP-9)				J Med Chem 46: 1811-23 (2003) Article DOI: 10.1021/jm020475w BindingDB Entry DOI: 10.7270/Q2TQ60W7
					More data for this Ligand-Target Pair
Interstitial collagenase (Homo sapiens (Human))	BDBM50127477 (2-(1,1-Dioxo-1,3,4,5-tetrahydro-1lambda*6*-benzo[f...) Show SMILES C[C@@H](N1CCNc2ccccc2S1(=O)=O)C(=O)NO Show InChI InChI=1S/C11H15N3O4S/c1-8(11(15)13-16)14-7-6-12-9-4-2-3-5-10(9)19(14,17)18/h2-5,8,12,16H,6-7H2,1H3,(H,13,15)/t8-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>4.95E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description In vitro inhibitory activity against broad spectrum matrix metalloprotease-1 (MMP-1)				J Med Chem 46: 1811-23 (2003) Article DOI: 10.1021/jm020475w BindingDB Entry DOI: 10.7270/Q2TQ60W7
					More data for this Ligand-Target Pair