BindingDB logo
myBDB logout

null

SMILES: CCCn1cnc2n(cnc2c1=O)[C@@H]1O[C@H](COC)[C@H](OP(C)([O-])=O)C1OC

InChI Key: InChIKey=SAOJGNFIJDGXSC-QEFZCKDJSA-M

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50127513   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Reverse transcriptase/RNaseH


(Human immunodeficiency virus 1)		BDBM50127513
PNG
((2R,3S,5R)-4-methoxy-2-(methoxymethyl)-5-(6-oxo-1-...)
Show SMILES CCCn1cnc2n(cnc2c1=O)[C@@H]1O[C@H](COC)[C@H](OP(C)([O-])=O)C1OC
Show InChI InChI=1S/C16H25N4O7P/c1-5-6-19-8-18-14-11(15(19)21)17-9-20(14)16-13(25-3)12(27-28(4,22)23)10(26-16)7-24-2/h8-10,12-13,16H,5-7H2,1-4H3,(H,22,23)/p-1/t10-,12+,13?,16-/m1/s1
PDB
MMDB

UniProtKB/TrEMBL

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 6.70E+3n/an/an/an/an/an/a



University of Utah

Curated by ChEMBL


Assay Description
Inhibitory activity of compound against reverse transcriptase (RT) in cell free RT.

J Med Chem 46: 1878-85 (2003)


Article DOI: 10.1021/jm0203276
BindingDB Entry DOI: 10.7270/Q25X29NG
More data for this
Ligand-Target Pair