BDBM50127709 CHEMBL3629689
SMILES: [Na+].[Na+].[Na+].Nc1ccn([C@@H]2O[C@H](COP([O-])(=O)OC(C3CCCC3)P([O-])([O-])=O)[C@@H](O)[C@H]2O)c(=O)n1
InChI Key: InChIKey=KOODYCJETOSSTB-MKFDKLCLSA-K
Data: 2 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
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Beta-galactoside alpha-2,6-sialyltransferase 1 (Homo sapiens (Human)) | BDBM50127709 (CHEMBL3629689) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | 5.85E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Peking University Curated by ChEMBL | Assay Description Inhibition of recombinant human N-terminal His-tagged ST6Gal-1 (44 to 406 residues) using CMP-Neu5Ac as substrate after 20 mins by UV/RP-HPLC method | J Med Chem 60: 2135-2141 (2017) Article DOI: 10.1021/acs.jmedchem.6b01644 BindingDB Entry DOI: 10.7270/Q2XP77Z0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta-galactoside alpha-2,6-sialyltransferase 1 (Homo sapiens (Human)) | BDBM50127709 (CHEMBL3629689) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | PubMed | 5.85E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Peking University Curated by ChEMBL | Assay Description Competitive inhibition of human recombinant ST6Gal-1 using CMP-Neu5Ac and p-nitrophenyl LacNAc as donar and acceptor by Lineweaver-Burk double recipr... | J Med Chem 58: 7972-90 (2015) BindingDB Entry DOI: 10.7270/Q20V8FMQ | |||||||||||
More data for this Ligand-Target Pair |