BDBM50127762 CHEMBL47170::Cyclobutanecarboxylic acid [2-(2,2,2-trifluoro-1-hydroxy-1-trifluoromethyl-ethyl)-naphthalen-1-yl]-amide

SMILES: OC(c1ccc2ccccc2c1NC(=O)C1CCC1)(C(F)(F)F)C(F)(F)F

InChI Key: InChIKey=PVDMPFVJYDPLCZ-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50127762   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sulfonylurea receptor 2, Kir6.2 (Homo sapiens (Human))	BDBM50127762 (CHEMBL47170 | Cyclobutanecarboxylic acid [2-(2,2,2...) Show SMILES OC(c1ccc2ccccc2c1NC(=O)C1CCC1)(C(F)(F)F)C(F)(F)F Show InChI InChI=1S/C18H15F6NO2/c19-17(20,21)16(27,18(22,23)24)13-9-8-10-4-1-2-7-12(10)14(13)25-15(26)11-5-3-6-11/h1-2,4,7-9,11,27H,3,5-6H2,(H,25,26)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	45	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Potassium channel opening activity in vitro using LtK cells transfected with Kir6.2/SUR2B exon 17				Bioorg Med Chem Lett 13: 1741-4 (2003) BindingDB Entry DOI: 10.7270/Q28S4P9V
					More data for this Ligand-Target Pair