BDBM50127834 1-Methyl-2-[4-(3-piperidin-1-yl-propoxy)-phenyl]-indolizine::CHEMBL50138

SMILES: Cc1c(cn2ccccc12)-c1ccc(OCCCN2CCCCC2)cc1

InChI Key: InChIKey=GGPIOTGDYGYNCP-UHFFFAOYSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50127834   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histamine H3 receptor (Homo sapiens (Human))	BDBM50127834 (1-Methyl-2-[4-(3-piperidin-1-yl-propoxy)-phenyl]-i...) Show SMILES Cc1c(cn2ccccc12)-c1ccc(OCCCN2CCCCC2)cc1 Show InChI InChI=1S/C23H28N2O/c1-19-22(18-25-16-6-3-8-23(19)25)20-9-11-21(12-10-20)26-17-7-15-24-13-4-2-5-14-24/h3,6,8-12,16,18H,2,4-5,7,13-15,17H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	16	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Botswana Curated by ChEMBL					Assay Description Antagonist activity at human histamine H3 receptor				Eur J Med Chem 46: 5237-57 (2011) Article DOI: 10.1016/j.ejmech.2011.08.042 BindingDB Entry DOI: 10.7270/Q2ZG6SNF
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50127834 (1-Methyl-2-[4-(3-piperidin-1-yl-propoxy)-phenyl]-i...) Show SMILES Cc1c(cn2ccccc12)-c1ccc(OCCCN2CCCCC2)cc1 Show InChI InChI=1S/C23H28N2O/c1-19-22(18-25-16-6-3-8-23(19)25)20-9-11-21(12-10-20)26-17-7-15-24-13-4-2-5-14-24/h3,6,8-12,16,18H,2,4-5,7,13-15,17H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	16	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research and Development L. L. C. Curated by ChEMBL					Assay Description Binding affinity towards human Histamine H3 receptor using [3H]-N-methyl-histamine as radioligand				Bioorg Med Chem Lett 13: 1767-70 (2003) BindingDB Entry DOI: 10.7270/Q21835V3
					More data for this Ligand-Target Pair